Fluorogenic Diels–Alder reactions of novel phencyclone derivatives

With the aim of obtaining fluorogenic Diels–Alder reactions, novel phencyclone derivatives were synthesized. In a short time and under convenient reaction conditions, the formation of Diels–Alder adducts was observed by color-change and up to 33-fold enhancement of fluorescence. The modification of...

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Bibliographic Details
Published in:Tetrahedron letters 2013-04, Vol.54 (14), p.1832-1834
Main Authors: Aydin, Engin Aytac, Altenbach, Hans-Josef
Format: Article
Language:English
Subjects:
Diels–Alder cycloaddition
Fluorescent labeling
Fluorogenic
Nucleosides
Citations: Items that this one cites
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Summary:With the aim of obtaining fluorogenic Diels–Alder reactions, novel phencyclone derivatives were synthesized. In a short time and under convenient reaction conditions, the formation of Diels–Alder adducts was observed by color-change and up to 33-fold enhancement of fluorescence. The modification of thymidine and deoxycytidine derivatives with a maleimide side chain and their usage in fluorogenic Diels–Alder reaction is also reported.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.01.095