A new fluorescent sensor for Cd2+ and its application in living cells imaging

[Display omitted] A novel, fluorescent sensor based on 2,7-dichlorofluorescein with aromatized diethylene triamine as ionophore was developed. Under physiological pH conditions, the sensor exhibited about 70-fold enhancement in fluorescence emission upon binding with Cd2+. It demonstrates that the s...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2015-03, Vol.56 (11), p.1322-1327
Main Authors: Liu, Xiao-yan, Liu, Da-ying, Qi, Jing, Cui, Zhi-gang, Chang, He-xi, He, Hua-rui, Yang, Guang-ming
Format: Article
Language:English
Subjects:
Cadmium
Cell imaging
Fluorescence sensor
Ionophore
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] A novel, fluorescent sensor based on 2,7-dichlorofluorescein with aromatized diethylene triamine as ionophore was developed. Under physiological pH conditions, the sensor exhibited about 70-fold enhancement in fluorescence emission upon binding with Cd2+. It demonstrates that the sensor can be used to detect Cd2+ in aqueous solution and it was successfully applied to image Cd2+ in living cells.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2015.02.010