An approach toward novel bioactive natural products antroquinonols: de novo construction of the carbocyclic core

[Display omitted] A new, short, approach toward bioactive antroquinonols has been conceptualized wherein the key carbocyclic core has been readily assembled employing disposable norbornyl scaffold as the regio- and stereo-director and a Wittig olefination based strategy is projected for appending th...

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Bibliographic Details
Published in:Tetrahedron letters 2015-10, Vol.56 (44), p.6030-6033
Main Authors: Modugu, Nagi Reddy, Mehta, Goverdhan
Format: Article
Language:English
Subjects:
Cyclohexanoid synthesis
Mitsunobu reaction
Regio- and stereoselective epoxidation
Retro-Diels–Alder reaction
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Summary:[Display omitted] A new, short, approach toward bioactive antroquinonols has been conceptualized wherein the key carbocyclic core has been readily assembled employing disposable norbornyl scaffold as the regio- and stereo-director and a Wittig olefination based strategy is projected for appending the farnesyl arm.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2015.09.043