Zinc oxide surface: a versatile nanoplatform for solvent-free synthesis of diverse isatin derivatives

[Display omitted] •Surface catalysis by ZnO nanodiscs is superior to other morphologies.•Diverse isatin derivatives were synthesized under solvent-free reactions.•The ZnO catalyst is reusable up to 5 cycles. Multicomponent reactions performed on the surface of nanostructured zinc oxide gave 3,3-bis(...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2016-08, Vol.57 (31), p.3472-3475
Main Authors: Kothandapani, Jagatheeswaran, Ganesan, Asaithampi, Mani, Ganesh Kumar, Kulandaisamy, Arockia Jayalatha, Rayappan, John Bosco Balaguru, Selva Ganesan, Subramaniapillai
Format: Article
Language:English
Subjects:
Multicomponent reaction
Solvent-free synthesis
Surface catalysis
Zinc oxide
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] •Surface catalysis by ZnO nanodiscs is superior to other morphologies.•Diverse isatin derivatives were synthesized under solvent-free reactions.•The ZnO catalyst is reusable up to 5 cycles. Multicomponent reactions performed on the surface of nanostructured zinc oxide gave 3,3-bis(indolyl)indolin-2-one and xanthene derivatives with excellent yields. Both Lewis acidic (Zn2+) and basic (O2−) sites on the surface of zinc oxide were utilized to perform the aforementioned transformations. The significance of surface catalysis was further proved by performing the experiment with surface masked zinc oxide. The developed zinc oxide nanocatalyst was reusable up to five times without significant loss in its activity.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2016.06.094