Dichloromethane as methylene donor for the one-pot synthesis of bisaryloxy methanes via Williamson etherification and Suzuki coupling

[Display omitted] •Facile one-pot reactions consist of DCM-based Williamson etherification and Suzuki coupling.•Novel bisaryloxy methane products.•Selective synthesis of products with both symmetrical and unsymmetrical structures. The multicomponent reactions of o-, m, or p-iodophenols, arylboronic...

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Bibliographic Details
Published in:Tetrahedron letters 2016-11, Vol.57 (46), p.5116-5119
Main Authors: Chen, Xuwen, Hu, Changfeng, Wan, Jie-Ping, Liu, Yunyun
Format: Article
Language:English
Subjects:
Bisaryloxy methanes
One-pot reaction
Palladium catalysis
Suzuki coupling
Williamson etherification
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Summary:[Display omitted] •Facile one-pot reactions consist of DCM-based Williamson etherification and Suzuki coupling.•Novel bisaryloxy methane products.•Selective synthesis of products with both symmetrical and unsymmetrical structures. The multicomponent reactions of o-, m, or p-iodophenols, arylboronic acids, and dichloromethane (DCM) have been designed for the synthesis of various bisaryloxy methanes via one-pot procedure consists of Williamson etherification and Suzuki coupling.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2016.10.023