Chromatographic techniques to determine conjugated linoleic acid isomers

Conjugated linoleic acid (CLA) is a complex mixture of positional and geometric isomers that contains a conjugated double-bond system and exhibits health-promoting attributes. Although cis-9 trans-11 is the predominant species in dairy foods and biological subtracts, there is a real need to determin...

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Bibliographic Details
Published in:TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2006-10, Vol.25 (9), p.917-926
Main Authors: de la Fuente, Miguel Angel, Luna, Pilar, Juárez, Manuela
Format: Article
Language:English
Subjects:
Ag +-HPLC
Analysis
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
CLA
Exact sciences and technology
Gas chromatographic methods
GC-MS
Isomer
Other chromatographic methods
Spectrometric and optical methods
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Summary:Conjugated linoleic acid (CLA) is a complex mixture of positional and geometric isomers that contains a conjugated double-bond system and exhibits health-promoting attributes. Although cis-9 trans-11 is the predominant species in dairy foods and biological subtracts, there is a real need to determine the CLA-isomer distribution, since the isomers may have different biological functions. This review covers the latest advances in the analytical techniques, mainly GC-MS and Ag +-HPLC, to determine the isomeric profile of CLA.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2006.04.012