Directed antibody-engineering techniques and their applications in food immunoassays

The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in im...

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Bibliographic Details
Published in:TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2011-02, Vol.30 (2), p.219-226
Main Authors: Markus, Vehniäinen, Janne, Leivo, Urpo, Lamminmäki
Format: Article
Language:English
Subjects:
Antibody
Directed antibody engineering
Food immunoassay
Food quality
Food safety
Immunoanalysis
immunoassays
Immunodiagnostics
recombinant antibodies
Recombinant antibody
safety assessment
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Description
Summary:The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2011.01.001