Loading…

Applications of particle-tracking analysis to the determination of size distributions and concentrations of nanoparticles in environmental, biological and food samples

The manufacture of nanoparticles (NPs) and nanomaterial-based products is rapidly increasing and their possible occurrence in environment, food or biological tissue is becoming of concern for ecological and human health. However, there is a lack of suitable methods to analyze and to characterize NPs...

Full description

Saved in:
Bibliographic Details
Published in:TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2011-03, Vol.30 (3), p.473-483
Main Authors: Gallego-Urrea, Julian A., Tuoriniemi, Jani, Hassellöv, Martin
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The manufacture of nanoparticles (NPs) and nanomaterial-based products is rapidly increasing and their possible occurrence in environment, food or biological tissue is becoming of concern for ecological and human health. However, there is a lack of suitable methods to analyze and to characterize NPs in low concentrations in complex matrixes. We compare several particle-tracking methods using video microscopy and a new technique called nanoparticle-tracking analysis (NTA). Video microscopy has been widely applied to investigate particle movement in biological samples, micro-rheology, and velocity profiles in fluids, whilst NTA was devised for determination of size distributions and concentrations in liquid samples. We critically discuss the advantages and the limitations of NTA for such applications.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2011.01.005