Desorption electrospray ionization mass spectrometry for food analysis

• Published in: TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2019-06, Vol.115, p.162-173
• Main Authors: Gentili, Alessandra, Fanali, Salvatore, Mainero Rocca, Lucia
• Format: Article
• Language: English
• Subjects: Ambient mass spectrometry; DAPCI-MS; DAPPI-MS; DESI-MS; Direct analysis; Food adulteration; Food characterization; Sample pre-treatment; Semi-quantitative and quantitative analysis
• ISSN: 0165-9936; 1879-3142
• DOI: 10.1016/j.trac.2019.04.015

Desorption electrospray ionization mass spectrometry (DESI-MS) has found applications in many fields. Unfortunately and despite many peculiarities, its use in food science is still in its infancy. This review focuses on both technical aspects and the different ways in which this interface has been exploited in food analysis. DESI signal's reliance on interface geometry, solvent composition, and analyte distribution is deeply evaluated and microscopic pictures of these phenomena are shown in order to provide a fundament to critically understand the overviewed works. Green aspects of the technique are also described, distinguishing between direct (no sample pretreatment) and indirect methods (minimal sample pretreatment). All papers published from the appearance of DESI interface on the market are examined. Authors' goal was to produce an organic and complete overview able to provide a clear critical opinion on the key issues, available methods and future developments in this field of study. [Display omitted] •Deep description of different approaches and solutions for a full exploitation of DESI interface.•Emphasis on technical aspects and particularly on signal behaviour.•Critical evaluation of the reviewed DESI-based projects.•In-depth discussion on the most important aspects of each work Focus on practical issues and solutions.