Advances in bimetallic materials and bimetallic oxide nanozymes: Synthesis, classification, catalytic mechanism and application in analytical chemistry

• Published in: TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2024-07, Vol.176, p.117757, Article 117757
• Main Authors: Wu, Yun-Yun, Tian, Xin, Jiang, Yuan, Ma, Hao-Yu, Wang, Wei, Zhang, Wen-Sheng, Martin, Jovan San, Yan, Yong, Qin, Dong-Dong, Han, Dong-Xue, Niu, Li
• Format: Article
• Language: English
• Subjects: Analytical application; Bimetallic; Colorimetric sensors; Enzyme mimetic activity; Nanozymes
• ISSN: 0165-9936
• DOI: 10.1016/j.trac.2024.117757

Bimetallic materials and bimetallic inorganics have the advantages of low preparation cost, stable performance, easy preservation and recycling, etc., which is the important materials of current nanozyme research. An in-depth understanding of the possible catalytic mechanisms from the aspect of material composition and structure will be helpful for the development of new and efficient nanozymes, which is of great significance for the rational regulation of nanozymes' activities. In this review, we systematically introduce the classification of bimetallic materials and bimetallic oxide nanozymes, their catalytic mechanisms, as well as the research progress in recent years in the fields of analytical chemistry, including colorimetric and electrochemical sensing, as well as biomedical analysis. We also present the current challenges faced by bimetal-containing nanozymes and future research priorities. This review is important for further understanding the nature of bimetallic nanozymes and for the development of novel nanomaterials with superior analytical functions. TOC Graphics. (Illustration adapted with permission from Ref. [19], Copyright (2022) Elsevier B.V.; [104], Copyright (2023) American Chemical Society; [45], Copyright (2019) Elsevier B.V.; [105], Copyright (2018) American Chemical Society; [130], Copyright (2020) Elsevier B. V. [131], Copyright (2020) Wiley-VCH GmbH). [Display omitted] •Recently developed bimetallic materials and bimetallic oxide nanozymes are summarized.•The mechanism of enzymatic reaction is presented.•The application in colorimetric sensing, environmental monitoring, and biomedical analysis are discussed in details.•Current challenges faced by bimetal-containing nanozymes and future research priorities are provided.