Long-Term Results for Liver Transplantation From Non–Heart-Beating Donors Mantained With Chest and Abdominal Compression-Decompression

The aim of this study was to evaluate long-term results after liver transplantation from non–heart-beating donors (NHBD) using the method of chest and abdominal compression-decompression to maintain donors. From December 1995 to November 2004, 10 NHBD were identified and maintained by means of the m...

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Bibliographic Details
Published in:Transplantation proceedings 2005-11, Vol.37 (9), p.3857-3858
Main Authors: Quintela, J., Gala, B., Baamonde, I., Fernández, C., Aguirrezabalaga, J., Otero, A., Suárez, F., Fernández, A., Gomez, M.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Medical sciences
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tissue, organ and graft immunology
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Summary:The aim of this study was to evaluate long-term results after liver transplantation from non–heart-beating donors (NHBD) using the method of chest and abdominal compression-decompression to maintain donors. From December 1995 to November 2004, 10 NHBD were identified and maintained by means of the method of chest and abdominal compression-decompression until family and judicial permission were granted. Nine donors were Maastricht type II and one was type IV. The mean age of donors was 40.5 years and the mean time under cardiopulmonary resuscitation (CPR) was 80 minutes. Orthotopic liver transplantation (OLT) was performed using these 10 liver grafts after a mean cold ischemia time of 561.5 minutes. All patients developed good posttransplant function, except for one patient who presented with primary nonfunction corrected with retransplantation. This complication was directly related to a long CPR time ( P < .01). After a mean follow-up of 57 months, only one patient died from a hepatitis C virus (HCV) recurrence. The rest of the patients have maintained good graft function over time. NHBD maintained with the method of chest and abdominal compression-decompression are a valid choice to increase the donor pool. Liver transplantation using these grafts has proven good long-term results, comparable to their heart-beating counterparts.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2005.10.039