A pilot study of a simple screening technique for estimation of salivary flow

Objectives The purpose of this study was to develop a simple screening technique for estimation of salivary flow and to test the usefulness of the method for determining decreased salivary flow. Study design A novel assay system comprising 3 spots containing 30 μg starch and 49.6 μg potassium iodide...

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Published in:Oral surgery, oral medicine, oral pathology, oral radiology and endodontics oral medicine, oral pathology, oral radiology and endodontics, 2009-09, Vol.108 (3), p.389-393
Main Authors: Kanehira, Takashi, DDS, PhD, Yamaguchi, Tomotaka, DDS, Takehara, Junji, DDS, PhD, Kashiwazaki, Haruhiko, DDS, PhD, Abe, Takae, DDS, Morita, Manabu, DDS, PhD, Asano, Kouzo, PhD, Fujii, Yoshinori, MD, Sakamoto, Wataru, MD
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Chromatography, Paper - instrumentation
Coloring Agents
Ethanol
Female
Humans
Hydrogen Peroxide
Male
Mass Screening - methods
Medical sciences
Otorhinolaryngology. Stomatology
Oxidants
Pilot Projects
Potassium Iodide
Reagent Kits, Diagnostic
Saliva - secretion
Secretory Rate - physiology
Solvents
Starch
Surgery
Xerostomia - diagnosis
Young Adult
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Summary:Objectives The purpose of this study was to develop a simple screening technique for estimation of salivary flow and to test the usefulness of the method for determining decreased salivary flow. Study design A novel assay system comprising 3 spots containing 30 μg starch and 49.6 μg potassium iodide per spot on filter paper and a coloring reagent, based on the color reaction of iodine-starch and theory of paper chromatography, was designed. We investigated the relationship between resting whole salivary rates and the number of colored spots on the filter produced by 41 hospitalized subjects. Results A significant negative correlation was observed between the number of colored spots and the resting salivary flow rate (n = 41; r = −0.803; P < .01). For all complaints of decreased salivary flow (n = 9) having cutoff values
ISSN:1079-2104
1528-395X
DOI:10.1016/j.tripleo.2009.04.019