Environmental Safety of the 180-W GreenLight Laser: A Pilot Study On Plume And Irrigating Fluids

• Published in: Urology (Ridgewood, N.J.) N.J.), 2021-08, Vol.154, p.227-232
• Main Authors: Ferrari, Giovanni, Ferrari, Anna Maria, Campobasso, Davide, Modenese, Alberto, Rijo, Enrique, Misrai, Vincent, Rosa, Roberto, Cindolo, Luca
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Air Pollution, Indoor - adverse effects; Air Pollution, Indoor - analysis; Humans; Lasers; Male; Middle Aged; Pilot Projects; Prospective Studies; Prostatectomy - methods; Prostatic Hyperplasia - surgery; Smoke - adverse effects; Smoke - analysis; Therapeutic Irrigation - methods
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2021.03.016

To analyze the chemical composition of the surgical smoke and the outflow irrigation fluid produced during a common endourological surgical procedure to treat benign prostatic obstruction (BPO). A prospective study was performed to analyze the surgical smoke generated during photoselective vaporization of the prostate (PVP) using the 180-W GL-XPS GreenLight Laser system. Surgical smoke samples were collected from 5 patients, and irrigation fluid samples were collected from 5 different patients. Qualitative organic compound determination was performed on both types of collected specimens using headspace-gas chromatography/mass spectrometry (HS-GC/MS) analysis. Four organic compounds were identified in the analyses of the smoke samples: tetradecane, hexadecane, 7-methylpentadecane and 2,6-dimethyleptadecane. In the analysis of fluid samples, 16 organic elements were identified. Interestingly, two compounds present in the first group (7-methylpentadecane and 2,6-dimethyleptadecane) were not detected in the fluid samples from the second group. None of the sixteen compounds detected in the fluids were present in all of the samples. Overall, seven of these compounds can be classified as toxic for acute exposure, while 4 others may represent a health hazard. We found that the different types of surgical smoke and irrigation fluids produced during PVP with a GreenLight Laser contain a limited number of organic compounds with a potential inhalation hazard. More studies are needed to understand the potential hazard for the exposed employees.