Use of perirectal hyaluronic acid spacer prior to radiotherapy in a pediatric patient with bladder rhabdomyosarcoma: a case report

Rhabdomyosarcoma(RMS) treatment involves surgery, chemotherapy, and radiotherapy. A radioprotective space between the bladder/prostate and rectum reduces post-radiation complications, as reported in adult patients. Objective: describe pediatric pre-radiotherapy perirectal hyaluronic acid (HA) spacer...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2023-11, Vol.181, p.136-140
Main Authors: Arceo-Olaiz, Ricardo, Smith, Edwin A, Stokes, Claire, Eaton, Bree R., Garcia-Roig, Michael
Format: Article
Language:English
Subjects:
Adult
Child
Humans
hyaluronic acid
Hyaluronic Acid - therapeutic use
Infant
Male
pediatric rhabdomyosarcoma
Pelvic Neoplasms
perirectal spacer
Prostatic Neoplasms
radiotherapy complications
Rhabdomyosarcoma - radiotherapy
Rhabdomyosarcoma, Embryonal
Urinary Bladder - diagnostic imaging
Urinary Bladder Neoplasms - drug therapy
Urinary Bladder Neoplasms - radiotherapy
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Summary:Rhabdomyosarcoma(RMS) treatment involves surgery, chemotherapy, and radiotherapy. A radioprotective space between the bladder/prostate and rectum reduces post-radiation complications, as reported in adult patients. Objective: describe pediatric pre-radiotherapy perirectal hyaluronic acid (HA) spacer injection for bladder/prostate RMS. We present a case of a 17-month-old male with bladder/prostate RMS. Before radiotherapy, an HA spacer was injected peri-rectally. Under general anesthesia, a transrectal ultrasound was positioned and 1 ml of HA spacer was injected into the perirectal space. No complications were reported at 6-month follow-up. This is the first report of pre-RT spacer injection for pediatric bladder/prostate RMS.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2023.06.018