Evaluation of hepatitis B vaccination status and immune response among health care workers in a tertiary care hospital in western India

Hepatitis B virus infection is still an important health problem worldwide. The risk of contracting HBV by health-care workers (HCWs) is higher than that of the general adult population. Seroprotection is defined as anti-HBs level 10mIU/ml or more following a successful three-dose vaccination course...

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Bibliographic Details
Published in:Vacunas (Barcelona. Internet. English ed.) 2021-05, Vol.22 (2), p.68-73
Main Authors: Mehta Tanmay, K., Shah Parul, D.
Format: Article
Language:English
Subjects:
Anti-HB
Anti-HBs
Antiviral immune response
Cobertura de la vacuna frente a la hepatitis B
Hepatitis B vaccination coverage
Hepatitis B vaccine
Respuesta inmune antiviral
Seroprotección
Seroprotection
Vacuna frente a la hepatitis B
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Summary:Hepatitis B virus infection is still an important health problem worldwide. The risk of contracting HBV by health-care workers (HCWs) is higher than that of the general adult population. Seroprotection is defined as anti-HBs level 10mIU/ml or more following a successful three-dose vaccination course. To find out the hepatitis B vaccination status and test immune response using anti-HBs titer among HCWs. We carried out a retrospective observational study of 218 serum samples from vaccinated HCWs tested for anti-HBs ELISA from January 2016 to December 2017. We collected demographic, health, and HBV vaccination details from test requisition forms. We found that 195 (89.44%) HCWs had received a complete course of HBV vaccination. 74.87% HCWs showed a protective level (10mIU/ml or more) of antibodies. We noted a statistically significant association between the protective antibody level and the complete course of vaccination (P
ISSN:2445-1460
2445-1460
DOI:10.1016/j.vacune.2020.09.002