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Spontaneous Raman bioimaging – Looking to 2050

Raman imaging has been employed for a wide range of biological sample analyses, is often chosen for its non-invasiveness, and ability to provide rich information from samples with minimal preparation requirements. In this paper we give a brief overview of the applications of spontaneous Raman imagin...

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Bibliographic Details
Published in:Vibrational spectroscopy 2024-03, Vol.131, p.103668, Article 103668
Main Authors: Hobro, Alison J., Smith, Nicholas I.
Format: Article
Language:English
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Summary:Raman imaging has been employed for a wide range of biological sample analyses, is often chosen for its non-invasiveness, and ability to provide rich information from samples with minimal preparation requirements. In this paper we give a brief overview of the applications of spontaneous Raman imaging in bioanalysis and then consider what Raman imaging in 2050 might look like. We discuss the state of Raman imaging around its inception, then provide a snapshot of current technology, then look towards 2050. We then discuss some of the potential bottlenecks for the continuing development of Raman imaging for biological sample analysis and, where appropriate, outline approaches to overcome these challenges.
ISSN:0924-2031
1873-3697
DOI:10.1016/j.vibspec.2024.103668