Biological removal of pharmaceuticals and personal care products during laboratory soil aquifer treatment simulation with different primary substrate concentrations

• Published in: Water research (Oxford) 2012-05, Vol.46 (7), p.2365-2375
• Main Authors: Onesios, Kathryn M., Bouwer, Edward J.
• Format: Article
• Language: English
• Subjects: acetates; Acetates - metabolism; Applied sciences; aquifers; Biodegradation; Biodegradation, Environmental; biofilm; Biofilms - growth & development; Cosmetics - metabolism; Emerging contaminants; Exact sciences and technology; filtration; Groundwater - microbiology; ibuprofen; ketoprofen; laboratory experimentation; Micropollutant; Molecular Structure; personal care products; Pharmaceutical Preparations - chemistry; Pharmaceutical Preparations - metabolism; Pollution; PPCPs; sand; sodium; soil; Soil Microbiology; surface water; toxicity; toxicity testing; valproic acid; Waste Disposal, Fluid - methods; wastewater treatment; Water Pollutants, Chemical - chemistry; Water Pollutants, Chemical - metabolism; Water Purification - methods; Water recycling; Water reuse; Water treatment and pollution
• ISSN: 0043-1354; 1879-2448
• DOI: 10.1016/j.watres.2012.02.001

Pharmaceuticals and personal care products (PPCPs) have been detected in bodies of water worldwide, yet their effects on the environment are not fully understood. Recent toxicity studies suggest that mixtures of PPCPs at low concentrations may be detrimental to exposed organisms, highlighting the need to remove PPCPs from wastewater treatment plant effluent before it is discharged to the environment. In this study, the utility of biofilm-based PPCP removal as a means to prevent environmental PPCP contamination was investigated. The removal of 14 PPCPs, each at an initial concentration of 10 μg/L, was studied in laboratory sand columns inoculated with wastewater treatment plant effluent. The examined PPCPs included biosol, biphenylol, p-chloro-m-cresol, p-chloro-m-xylenol, chlorophene, sodium diclofenac, gabapentin, gemfibrozil, 5-fluorouracil, ibuprofen, ketoprofen, naproxen, triclosan, and valproic acid. Ten of the PPCPs were removed by greater than 95% during column passage, while the four other compounds proved more recalcitrant. The effect of the concentration (either 50 or 1000 μg/L) of an easily degradable primary substrate (acetate) supplied along with the mixture of PPCPs was examined. Most of the tested PPCPs were removed consistently by the biofilms regardless of the concentration of acetate, although the extent of removal for three compounds showed dependence on acetate concentration, and two behaved with no reproducible pattern over time. Biofilm protein measurements indicated that the mixture of PPCPs supplied to columns suppressed biofilm growth, suggesting toxicity of the PPCPs to the biofilm communities. This laboratory-scale experiment suggests that biofilm-based water treatment strategies, such as soil aquifer treatment and slow sand filtration, may be well-suited for the removal of many PPCPs from impacted water. [Display omitted] ► We studied the biotransformation of PPCPs in bioactive lab sand columns. ► Many of the PPCPs we studied were removed by more than 95% in the biofilm columns. ► Most of our PPCPs’ biotransformations were independent of acetate concentration. ► The mixture of PPCPs supplied to columns suppressed biofilm growth. ► Biofilm-based water treatments can be effective for PPCP removal.