Predictors and Rates of Delayed Symptomatic Hyponatremia after Transsphenoidal Surgery: A Systemastic Review

Delayed symptomatic hyponatremia (DSH) is a known complication of transsphenoidal surgery that can lead to prolonged hospital stay, readmission, and in rare cases, death. Many potential predictors for development of DSH have been investigated. A better understanding of DSH risk can lead to better pa...

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Bibliographic Details
Published in:World neurosurgery 2016-04, Vol.88, p.1-6
Main Authors: Cote, David J., Alzarea, Abdulaziz, Acosta, Michael A., Hulou, Mohamed Maher, Huang, Kevin T., Almutairi, Hamoud, Alharbi, Ahmad, Zaidi, Hasan A., Algrani, Majed, Alatawi, Ahmed, Mekary, Rania A., Smith, Timothy R.
Format: Article
Language:English
Subjects:
Complications
Endoscopic surgery
Hyponatremia
Systematic review
Transsphenoidal surgery
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Summary:Delayed symptomatic hyponatremia (DSH) is a known complication of transsphenoidal surgery that can lead to prolonged hospital stay, readmission, and in rare cases, death. Many potential predictors for development of DSH have been investigated. A better understanding of DSH risk can lead to better patient outcomes. We performed a systematic review to determine the rates and predictors of DSH after both endoscopic transsphenoidal surgery and microscopic transsphenoidal surgery. A systematic search of the literature was conducted using MEDLINE/PUBMED, EMBASE, and Cochrane databases. Inclusion criteria were 1) case series with at least 10 cases reported, 2) adult patients who underwent eTSS or mTSS for pituitary tumors, and 3) reported occurrence of DSH (defined as serum sodium level
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2016.01.022