Cervical Spine Chondrosarcoma in an Adult with a History of Wilms Tumor

We report the first case of cervical spine chondrosarcoma in a Wilms tumor survivor. A 52-year-old female patient presented with myelopathic symptoms including poor balance, difficulty walking, and numbness of both feet. A magnetic resonance imaging of the spine showed a mass at the right C7-T1 fora...

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Bibliographic Details
Published in:World neurosurgery 2020-12, Vol.144, p.117-120
Main Authors: Im, Jacob, Soliman, Mohamed A.R., Alkhamees, Abdullah F., Eaton, Sydney, Quint, Elise, Shahab, Saba, O'Connor, Avalon, Haberfellner, Erika, Dyer, Erin
Format: Article
Language:English
Subjects:
Cervical
Cervical Vertebrae
Chondrosarcoma
Chondrosarcoma - complications
Decompression, Surgical - methods
Female
Humans
Kidney Neoplasms - complications
Magnetic Resonance Imaging
Middle Aged
Nephroblastoma
Spinal Cord Compression - etiology
Spinal Cord Compression - surgery
Spinal Fusion
Spinal Neoplasms - complications
Spine
Wilms tumor
Wilms Tumor - complications
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Summary:We report the first case of cervical spine chondrosarcoma in a Wilms tumor survivor. A 52-year-old female patient presented with myelopathic symptoms including poor balance, difficulty walking, and numbness of both feet. A magnetic resonance imaging of the spine showed a mass at the right C7-T1 foramen causing significant cord compression. The patient's symptoms improved after posterior decompression and fusion with excision of the tumor. Through our experience with this case, we would like to suggest a possible unknown genetic syndrome predisposing patients with Wilms tumor to chondrosarcoma as secondary neoplasms. We would also like to re-emphasize the need for vigilance when assessing patients with a history of Wilms tumor.
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2020.08.192