Clinical characteristics and prognosis of ultra high-risk gestational trophoblastic neoplasia patients: A retrospective cohort study

Highlights • Ultra high-risk gestational trophoblastic neoplasia patients have a poor prognosis. • The FAEV regimen is effective chemotherapy with manageable toxicity for GTN. • Prognosis-related risk factors for ultra high-risk GTN patients are revealed.

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Bibliographic Details
Published in:Gynecologic oncology 2017-07, Vol.146 (1), p.81-86
Main Authors: Kong, Yujia, Yang, Junjun, Jiang, Fang, Zhao, Jun, Ren, Tong, Li, Jie, Wang, Xiaoyu, Feng, Fengzhi, Wan, Xirun, Xiang, Yang
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Chemotherapy
Cohort Studies
Dactinomycin - administration & dosage
Etoposide - administration & dosage
Female
Floxuridine - administration & dosage
Gestational Trophoblastic Disease - diagnosis
Gestational Trophoblastic Disease - drug therapy
Gestational trophoblastic neoplasia
Hematology, Oncology and Palliative Medicine
Humans
Middle Aged
Obstetrics and Gynecology
Pregnancy
Prognosis
Retrospective Studies
Risk Factors
Salvage Therapy
Survival
Ultra high-risk
Vincristine - administration & dosage
Young Adult
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Description
Summary:Highlights • Ultra high-risk gestational trophoblastic neoplasia patients have a poor prognosis. • The FAEV regimen is effective chemotherapy with manageable toxicity for GTN. • Prognosis-related risk factors for ultra high-risk GTN patients are revealed.
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2017.04.010