Age, treatment and prognosis of patients with squamous cell vulvar cancer (VSCC) - analysis of the AGO-CaRE-1 study

Despite an increasing incidence with simultaneous decreasing age of onset, vulvar squamous cell carcinoma (VSCC) is still a disease that mainly effects the elderly population. Data on the association of age with prognosis and treatment patterns in VSCC are sparse. This is an analysis of the AGO-CaRE...

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Bibliographic Details
Published in:Gynecologic oncology 2021-05, Vol.161 (2), p.442-448
Main Authors: Prieske, Katharina, Woelber, Linn, Muallem, Mustafa Zelal, Eulenburg, Christine, Jueckstock, Julia Kathrin, Hilpert, Felix, de Gregorio, Nikolaus, Iborra, Severine, Ignatov, Atanas, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans-Georg, Baumann, Klaus, Beckmann, Matthias, Mustea, Alexander, Meier, Werner, Harter, Philipp, Wimberger, Pauline, Sehouli, Jalid, Mahner, Sven
Format: Article
Language:English
Subjects:
Age
Elderly
HPV
Lichen sclerosus
TP53
Vulvar cancer
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Summary:Despite an increasing incidence with simultaneous decreasing age of onset, vulvar squamous cell carcinoma (VSCC) is still a disease that mainly effects the elderly population. Data on the association of age with prognosis and treatment patterns in VSCC are sparse. This is an analysis of the AGO-CaRE-1 cohort. Patients with VSCC (FIGO stage ≥1B), treated at 29 cancer centers in Germany from 1998 to 2008, were included in a centralized database (n = 1618). In this subgroup analysis patients were analyzed according to age [
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2021.02.025