Acute phase proteins: a review of their function, behaviour and measurement in chickens

This review brings together and consolidates the large amount of research on acute phase proteins (APPs) that has been undertaken in chickens. Acute phase proteins are secreted from the liver as a result of inflammation or infection that can be measured in plasma. They have been well-characterised i...

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Bibliographic Details
Published in:World's poultry science journal 2014-03, Vol.70 (1), p.27-44
Main Authors: O'REILLY, E.L., ECKERSALL, P.D.
Format: Article
Language:English
Subjects:
acute phase protein
Animal species
biomarker
chicken
Chickens
infection
Poultry
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Summary:This review brings together and consolidates the large amount of research on acute phase proteins (APPs) that has been undertaken in chickens. Acute phase proteins are secreted from the liver as a result of inflammation or infection that can be measured in plasma. They have been well-characterised in other farm animal species and have been measured in a wide variety of poultry research areas. The acceleration in chicken APP research is in response to increased interest in ways the immune responses of the chicken can be measured and compared during infection or environmental or nutritional changes. All APPs that have been identified and characterised in chickens are described in the following review and their responses during infection discussed. The APPs are tabulated with basal values and classification to provide a comparative and useful reference. The ways APPs can be measured in chickens and the assays available are also described. This review will detail the functions of the positive APPs in chickens and their behaviour during an APR.
ISSN:0043-9339
1743-4777
DOI:10.1017/S0043933914000038