Method of Addition of Bromocriptine to the Drug Regime of Patients with Advanced Parkinson’s Disease

Using a method of a gradual increase of bromocriptine with a concomitant reduction of Sinemet® (levodopa 250 mg + carhidopa 25 mg), 19 patients with advanced Parkinson’s disease have been treated for periods of up to 22 months and 16 of them have shown improvements of varying degrees. Eighteen patie...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of neurological sciences 1981-02, Vol.8 (1), p.31-34
Main Authors: Grimes, J. David, Hassan, Mohamed N.
Format: Article
Language:English
Subjects:
Aged
Bromocriptine - administration & dosage
Bromocriptine - adverse effects
Carbidopa - administration & dosage
Drug Combinations
Drug Therapy, Combination
Female
Humans
Levodopa - administration & dosage
Male
Middle Aged
Parkinson Disease - diagnosis
Parkinson Disease - drug therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Using a method of a gradual increase of bromocriptine with a concomitant reduction of Sinemet® (levodopa 250 mg + carhidopa 25 mg), 19 patients with advanced Parkinson’s disease have been treated for periods of up to 22 months and 16 of them have shown improvements of varying degrees. Eighteen patients were able to tolerate bromocriptine addition, with early transient adverse effects occurring in seven cases. In contrast to several previously reported studies, it was found necessary to withdraw bromocriptine in only one case. With the drugs currently available, bromocriptine has a role in the management of patients with advanced Parkinson’s disease. The method described here may allow a greater number of patients to be given a trial with this drug.
ISSN:0317-1671
2057-0155
DOI:10.1017/S0317167100042803