Low Magnetic Field Induced Surface Enhanced Transient Spin-Trajectory Modulation of a Prototype Anticancer Drug Sanguinarine on a Single Domain Superparamagnetic Nanosurface

The role of the single-domain ferrimagnetic nanostructure and the associated surface for many fold magnetic-field-induced surface enhanced transient spin-trajectory modulation is a new venture in molecular spin dynamics. Though the interconversion between spin isomers in the excited state is often f...

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Published in:Journal of physical chemistry. C 2018-09, Vol.122 (36), p.20619-20631
Main Authors: Chakraborty, Sudeshna Das, Sau, Abhishek, Maity, Arnab, Pal, Uttam, Sengupta, Chaitrali, Bhattacharya, Maireyee, Bhattacharjee, Gourab, Banik, Sanjib, Satpati, Biswarup, Basu, Samita, Senapati, Dulal
Format: Article
Language:English
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Summary:The role of the single-domain ferrimagnetic nanostructure and the associated surface for many fold magnetic-field-induced surface enhanced transient spin-trajectory modulation is a new venture in molecular spin dynamics. Though the interconversion between spin isomers in the excited state is often forbidden by the spin selection rule, hopping between two spin trajectory surface is quite probable due to their high magnetic-field induced spin-interconversion. This spin-interconversion-induced conical intersection is mainly governed by the spin–orbit (L-S) coupling. The extent of spin-interconversion which controls their spin degeneracy or relative population beyond the molecular field can also be efficiently regulated by inducing a large magnetic moment in a nearfield configuration. In the present set of experiments, a large magnetic field antenna has been launched by external low magnetic-field-induced single-domain magnetic moment alignment of individual constituent atoms arranged inside a ferrimagnetic nanostructure which generates a superparamagnetic nanoarchitecture to push the programmable transient spin-trajectory modulation for surface adsorbed sanguinarine (Sgr), a known small molecule anticancer drug, through enhanced population of the spin-modulated component. Along with spin-interconversion, the distribution and the stabilization of radical formation in different solvent environments also play a pivotal role to control the overall transient spin trajectory population.
ISSN:1932-7447
1932-7455
DOI:10.1021/acs.jpcc.8b06129