Stimulus-Responsive Release from Poly(ferrocenylsilane) Nanocontainers

Redox-responsive poly­(ferrocenylsilane) (PFS) is used to construct nanocontainers that can be loaded with hydrophobic cargo by a miniemulsion approach. The resulting structures comprise a solid shell surrounding a liquid oil core and have diameters of approximately 470 nm with a shell thickness of...

Full description

Saved in:
Bibliographic Details
Published in:Macromolecules 2016-01, Vol.49 (1), p.105-109
Main Authors: Thomi, Laura, Schaefer, Philipp, Landfester, Katharina, Wurm, Frederik R
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Redox-responsive poly­(ferrocenylsilane) (PFS) is used to construct nanocontainers that can be loaded with hydrophobic cargo by a miniemulsion approach. The resulting structures comprise a solid shell surrounding a liquid oil core and have diameters of approximately 470 nm with a shell thickness of ca. 29 nm. The electrochemical behavior of the ferrocene group is investigated using cyclic voltammetry. Electrochemical oxidation and the thereby caused change of container morphology are shown. Hydrophobic molecules (Nile Red and 2-propylpyiridine) are loaded into the nanocontainers and can be released upon oxidation of the shell material. The oxidation is achieved chemically by the addition of hydrogen peroxide or by the enzymatic oxidation of glucose to release 2-propylpyridine over a period of time.
ISSN:0024-9297
1520-5835
DOI:10.1021/acs.macromol.5b02367