Fabrication of Antimicrobial Films Based on Cross-Linked Chitosan Nanocomposite in Food Packaging Applications

This study aims to develop a novel nanocomposite film by modifying chitosan with citric acid and reinforcing it with ZnO nanoparticles. The film’s surface was examined using FE-SEM/EDX and characterized through XPS, TGA, UV–vis, and mechanical testing. 1H NMR and FTIR spectroscopy analysis confirmed...

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Published in:ACS food science & technology 2025-01, Vol.5 (1), p.336-349
Main Authors: Rani, Raj, Saini, Rachit, Patel, Manoj Kumar, Gumber, Sakshi, Mazumder, Koushik, Deep, Akash, Nayak, Manoj Kumar
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container_title ACS food science & technology
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creator Rani, Raj
Saini, Rachit
Patel, Manoj Kumar
Gumber, Sakshi
Mazumder, Koushik
Deep, Akash
Nayak, Manoj Kumar
description This study aims to develop a novel nanocomposite film by modifying chitosan with citric acid and reinforcing it with ZnO nanoparticles. The film’s surface was examined using FE-SEM/EDX and characterized through XPS, TGA, UV–vis, and mechanical testing. 1H NMR and FTIR spectroscopy analysis confirmed the cross-link between chitosan and citric acid. The CS/CA@ZnO nanocomposite film showed a 25% increase in tensile strength and a 5-fold increase in elongation at break, with enhanced barrier properties against water vapor and antioxidant properties compared to pure chitosan. Furthermore, the zone of inhibition of nanocomposite film against Escherichia coli, Pseudomonas aeruginosa , and Staphylococcus aureus were 16 ± 1.31, 20 ± 1.25, and 18 ± 0.76 mm, respectively. Moreover, the cell viability of the RAW cell line on the surface of the nanocomposite film was 96.29 ± 1.12%, indicating excellent biocompatibility and holds significant potential for future use in the sustainable food packaging industry.
doi_str_mv 10.1021/acsfoodscitech.4c00865
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title Fabrication of Antimicrobial Films Based on Cross-Linked Chitosan Nanocomposite in Food Packaging Applications
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