Efficient Mechano-Enzymatic Hydrolysis of Polylactic Acid under Moist-Solid Conditions

Quantitative mechano-enzymatic depolymerization of polylactic acid to lactic acid was achieved at 55 °C using the Humicola insolens cutinase enzyme in moist-solid reaction mixtures. The resulting lactic acid was easily recovered, and the crude product was pure enough to be used in further synthesis...

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Bibliographic Details
Published in:ACS sustainable chemistry & engineering 2023-07, Vol.11 (27), p.9924-9931
Main Authors: Pérez-Venegas, Mario, Friščić, Tomislav, Auclair, Karine
Format: Article
Language:English
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Summary:Quantitative mechano-enzymatic depolymerization of polylactic acid to lactic acid was achieved at 55 °C using the Humicola insolens cutinase enzyme in moist-solid reaction mixtures. The resulting lactic acid was easily recovered, and the crude product was pure enough to be used in further synthesis of a value-added compound, a known benzimidazole-based drug precursor. The presented mechano-enzymatic depolymerization strategy enables the closed-loop recycling of untreated polylactic acid under mild conditions, using a renewable, non-toxic catalyst and producing minimum solvent waste.
ISSN:2168-0485
2168-0485
DOI:10.1021/acssuschemeng.2c06847