Metabolic activation of 1-methyl-3-amino-5H-pyrido[4,3-b]indole and several structurally related mutagens

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Bibliographic Details
Published in:Biochemistry (Easton) 1981-01, Vol.20 (2), p.298-305
Main Authors: Pezzuto, John M, Moore, Patrick D, Hecht, Sidney M
Format: Article
Language:English
Subjects:
Animals
Biotransformation
Carbolines - metabolism
Carbolines - pharmacology
Chemical Phenomena
Chemistry
DNA
Indoles - pharmacology
Methionine
Methods
Methylcholanthrene - pharmacology
Microsomes, Liver - drug effects
Microsomes, Liver - metabolism
Mutagenicity Tests
Mutagens
Rats
Salmonella typhimurium - drug effects
Structure-Activity Relationship
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ISSN:0006-2960
1520-4995
DOI:10.1021/bi00505a011