Solubility of Dioxopromethazine Hydrochloride in Different Solvents

The solubilities of dioxopromethazine hydrochloride (DPZ) in water, acetic acid, ethanol, methanol, N,N-dimethylformamide, N-methyl ketopyrrolidide, and acetone between (278 and 328) K were measured using a laser monitoring observation technique. Results of these measurements were correlated with a...

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Bibliographic Details
Published in:Journal of chemical and engineering data 2008-01, Vol.53 (1), p.301-302
Main Authors: Li, Qun-Sheng, Yi, Zheng-Ming, Su, Ming-Gao, Wang, Shui, Wu, Xiao-Hua
Format: Article
Language:English
Subjects:
Biological and medical sciences
General pharmacology
Medical sciences
Pharmacology. Drug treatments
Physicochemical properties. Structure-activity relationships
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Summary:The solubilities of dioxopromethazine hydrochloride (DPZ) in water, acetic acid, ethanol, methanol, N,N-dimethylformamide, N-methyl ketopyrrolidide, and acetone between (278 and 328) K were measured using a laser monitoring observation technique. Results of these measurements were correlated with a semiempirical equation. For seven solvents studied, the data are well fitted with a semiempirical equation.
ISSN:0021-9568
1520-5134
DOI:10.1021/je700453v