Determination of Dissociation Constants of Some Hydroxylated Benzoic and Cinnamic Acids in Water from Mobility and Spectroscopic Data Obtained by CE-DAD

In this study, the dissociation constants of a series of phenolic acids, including benzoic acid, four hydroxylated derivatives (p-hydroxybenzoic, protocatechuic, vanillic, and gallic), and four hydroxylated cinnamic acid derivatives (p-coumaric, caffeic, ferulic, and sinapinic) have been determined...

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Bibliographic Details
Published in:Journal of chemical and engineering data 2009-03, Vol.54 (3), p.807-811
Main Authors: Ozkorucuklu, Sabriye P, Beltrán, José L, Fonrodona, Gemma, Barrón, Dolores, Alsancak, Güleren, Barbosa, José
Format: Article
Language:English
Subjects:
Chemistry
Exact sciences and technology
Noncondensed benzenic compounds
Organic chemistry
Preparations and properties
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Summary:In this study, the dissociation constants of a series of phenolic acids, including benzoic acid, four hydroxylated derivatives (p-hydroxybenzoic, protocatechuic, vanillic, and gallic), and four hydroxylated cinnamic acid derivatives (p-coumaric, caffeic, ferulic, and sinapinic) have been determined in water by capillary electrophoresis (CE) from the electrophoretic mobilities at different pH value. The pK a values have also been obtained from the absorbance spectra at the maximum of the electrophoretic peaks, which were measured with a diode-array detector (CE-DAD methodology). The pK a values obtained from both methodologies (CE and CE-DAD) have been compared with those previously published in the literature and also with the values predicted by the SPARC online pK a calculator.
ISSN:0021-9568
1520-5134
DOI:10.1021/je800595x