Loading…
Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae)
Essential oils of Coriandrum sativum L. and Carum carvi L. fruits were analyzed by gas chromatography−mass spectrometry and assayed for their in vitro and in vivo antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl4) damage. The in vitro antioxidant activity was evalua...
Saved in:
| Published in: | Journal of agricultural and food chemistry 2010-08, Vol.58 (15), p.8848-8853 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13 |
|---|---|
| cites | cdi_FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13 |
| container_end_page | 8853 |
| container_issue | 15 |
| container_start_page | 8848 |
| container_title | Journal of agricultural and food chemistry |
| container_volume | 58 |
| creator | Samojlik, Isidora Lakić, Neda Mimica-Dukić, Neda Đaković-Švajcer, Kornelia Božin, Biljana |
| description | Essential oils of Coriandrum sativum L. and Carum carvi L. fruits were analyzed by gas chromatography−mass spectrometry and assayed for their in vitro and in vivo antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl4) damage. The in vitro antioxidant activity was evaluated as a free radical scavenging capacity (RSC), measured as scavenging activity of the essential oils on 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and OH radicals and effects on lipid peroxidation (LP) in two systems of induction. Some liver biochemical parameters were determined in animals pretreated with essential oils and later intoxicated with CCl4 to assess in vivo hepatoprotective effect. Tested essential oils were able to reduce the stable DPPH• in a dose-dependent manner and to neutralize H2O2, reaching 50% neutralization with IC50 values of |
| doi_str_mv | 10.1021/jf101645n |
| format | article |
| fullrecord | <record><control><sourceid>acs_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1021_jf101645n</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>a68579799</sourcerecordid><originalsourceid>FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13</originalsourceid><addsrcrecordid>eNptkE1OwzAQhS0EglJYcAHIBokuAjNJHKfLqgKKVKlIwDqaODZylSaRnRZ6BG6N-wNs2Hhm_L55Gj3GLhBuESK8m2sETBNeH7Ae8ghCjpgdsh54Mcx4iifs1Lk5AGRcwDE7iSCFTETDHvsa1Z1pPk1JdRdQXQYT1VLXtLbplOzMSgXPvvMMVUGjg3vn9sPMVG7zM26s8XvKBjf71i4XgSO_6-v0drB1HZOlD1p7hjayJLsyW_Fm1BqSitTgjB1pqpw639c-e3u4fx1Pwuns8Wk8moaUiKQLU6lAl5kQCRWqVAS64AqF0gJ0nBQSRDwUw1RpkP7hGPMhSD8jB0mkMe6zwc5X2sY5q3TeWrMgu84R8k2c-W-cnr3cse2yWKjyl_zJzwPXe4CcpEpbqqVxf1yMEMcZeO5qx2lqcnq3nnl7iQBjwEykaZL8OZF0-bxZ2tqH8M9J37ztksk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae)</title><source>American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)</source><creator>Samojlik, Isidora ; Lakić, Neda ; Mimica-Dukić, Neda ; Đaković-Švajcer, Kornelia ; Božin, Biljana</creator><creatorcontrib>Samojlik, Isidora ; Lakić, Neda ; Mimica-Dukić, Neda ; Đaković-Švajcer, Kornelia ; Božin, Biljana</creatorcontrib><description>Essential oils of Coriandrum sativum L. and Carum carvi L. fruits were analyzed by gas chromatography−mass spectrometry and assayed for their in vitro and in vivo antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl4) damage. The in vitro antioxidant activity was evaluated as a free radical scavenging capacity (RSC), measured as scavenging activity of the essential oils on 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and OH radicals and effects on lipid peroxidation (LP) in two systems of induction. Some liver biochemical parameters were determined in animals pretreated with essential oils and later intoxicated with CCl4 to assess in vivo hepatoprotective effect. Tested essential oils were able to reduce the stable DPPH• in a dose-dependent manner and to neutralize H2O2, reaching 50% neutralization with IC50 values of <2.5 μL/mL for Carvi aetheroleum and 4.05 μL/mL for Coriandri aetheroleum. Caraway essential oil strongly inhibited LP in both systems of induction, whereas coriander essential oil exhibited prooxidant activity. In vivo investigation conferred leak of antioxidative capacity of coriander essential oil, whereas the essential oil of caraway appeared promising for safe use in folk medicine and the pharmaceutical and food industries.</description><identifier>ISSN: 0021-8561</identifier><identifier>EISSN: 1520-5118</identifier><identifier>DOI: 10.1021/jf101645n</identifier><identifier>PMID: 20608729</identifier><identifier>CODEN: JAFCAU</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Animals ; antioxidant activity ; Antioxidants - administration & dosage ; Antioxidants - analysis ; Aroma and flavouring agent industries ; Biological and medical sciences ; caraway ; Carum - chemistry ; Carum carvi ; Coriandrum - chemistry ; Coriandrum sativum ; essential oils ; food analysis ; Food Chemistry/Biochemistry ; food composition ; Food industries ; Fundamental and applied biological sciences. Psychology ; hepatoprotective effect ; Lipid Peroxidation - drug effects ; Liver - drug effects ; Liver - metabolism ; Male ; Mice ; Oils, Volatile - administration & dosage ; Oils, Volatile - analysis ; Plant Oils - administration & dosage ; Plant Oils - analysis ; Protective Agents</subject><ispartof>Journal of agricultural and food chemistry, 2010-08, Vol.58 (15), p.8848-8853</ispartof><rights>Copyright © 2010 American Chemical Society</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13</citedby><cites>FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23103380$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20608729$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Samojlik, Isidora</creatorcontrib><creatorcontrib>Lakić, Neda</creatorcontrib><creatorcontrib>Mimica-Dukić, Neda</creatorcontrib><creatorcontrib>Đaković-Švajcer, Kornelia</creatorcontrib><creatorcontrib>Božin, Biljana</creatorcontrib><title>Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae)</title><title>Journal of agricultural and food chemistry</title><addtitle>J. Agric. Food Chem</addtitle><description>Essential oils of Coriandrum sativum L. and Carum carvi L. fruits were analyzed by gas chromatography−mass spectrometry and assayed for their in vitro and in vivo antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl4) damage. The in vitro antioxidant activity was evaluated as a free radical scavenging capacity (RSC), measured as scavenging activity of the essential oils on 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and OH radicals and effects on lipid peroxidation (LP) in two systems of induction. Some liver biochemical parameters were determined in animals pretreated with essential oils and later intoxicated with CCl4 to assess in vivo hepatoprotective effect. Tested essential oils were able to reduce the stable DPPH• in a dose-dependent manner and to neutralize H2O2, reaching 50% neutralization with IC50 values of <2.5 μL/mL for Carvi aetheroleum and 4.05 μL/mL for Coriandri aetheroleum. Caraway essential oil strongly inhibited LP in both systems of induction, whereas coriander essential oil exhibited prooxidant activity. In vivo investigation conferred leak of antioxidative capacity of coriander essential oil, whereas the essential oil of caraway appeared promising for safe use in folk medicine and the pharmaceutical and food industries.</description><subject>Animals</subject><subject>antioxidant activity</subject><subject>Antioxidants - administration & dosage</subject><subject>Antioxidants - analysis</subject><subject>Aroma and flavouring agent industries</subject><subject>Biological and medical sciences</subject><subject>caraway</subject><subject>Carum - chemistry</subject><subject>Carum carvi</subject><subject>Coriandrum - chemistry</subject><subject>Coriandrum sativum</subject><subject>essential oils</subject><subject>food analysis</subject><subject>Food Chemistry/Biochemistry</subject><subject>food composition</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>hepatoprotective effect</subject><subject>Lipid Peroxidation - drug effects</subject><subject>Liver - drug effects</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Mice</subject><subject>Oils, Volatile - administration & dosage</subject><subject>Oils, Volatile - analysis</subject><subject>Plant Oils - administration & dosage</subject><subject>Plant Oils - analysis</subject><subject>Protective Agents</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNptkE1OwzAQhS0EglJYcAHIBokuAjNJHKfLqgKKVKlIwDqaODZylSaRnRZ6BG6N-wNs2Hhm_L55Gj3GLhBuESK8m2sETBNeH7Ae8ghCjpgdsh54Mcx4iifs1Lk5AGRcwDE7iSCFTETDHvsa1Z1pPk1JdRdQXQYT1VLXtLbplOzMSgXPvvMMVUGjg3vn9sPMVG7zM26s8XvKBjf71i4XgSO_6-v0drB1HZOlD1p7hjayJLsyW_Fm1BqSitTgjB1pqpw639c-e3u4fx1Pwuns8Wk8moaUiKQLU6lAl5kQCRWqVAS64AqF0gJ0nBQSRDwUw1RpkP7hGPMhSD8jB0mkMe6zwc5X2sY5q3TeWrMgu84R8k2c-W-cnr3cse2yWKjyl_zJzwPXe4CcpEpbqqVxf1yMEMcZeO5qx2lqcnq3nnl7iQBjwEykaZL8OZF0-bxZ2tqH8M9J37ztksk</recordid><startdate>20100811</startdate><enddate>20100811</enddate><creator>Samojlik, Isidora</creator><creator>Lakić, Neda</creator><creator>Mimica-Dukić, Neda</creator><creator>Đaković-Švajcer, Kornelia</creator><creator>Božin, Biljana</creator><general>American Chemical Society</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20100811</creationdate><title>Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae)</title><author>Samojlik, Isidora ; Lakić, Neda ; Mimica-Dukić, Neda ; Đaković-Švajcer, Kornelia ; Božin, Biljana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Animals</topic><topic>antioxidant activity</topic><topic>Antioxidants - administration & dosage</topic><topic>Antioxidants - analysis</topic><topic>Aroma and flavouring agent industries</topic><topic>Biological and medical sciences</topic><topic>caraway</topic><topic>Carum - chemistry</topic><topic>Carum carvi</topic><topic>Coriandrum - chemistry</topic><topic>Coriandrum sativum</topic><topic>essential oils</topic><topic>food analysis</topic><topic>Food Chemistry/Biochemistry</topic><topic>food composition</topic><topic>Food industries</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>hepatoprotective effect</topic><topic>Lipid Peroxidation - drug effects</topic><topic>Liver - drug effects</topic><topic>Liver - metabolism</topic><topic>Male</topic><topic>Mice</topic><topic>Oils, Volatile - administration & dosage</topic><topic>Oils, Volatile - analysis</topic><topic>Plant Oils - administration & dosage</topic><topic>Plant Oils - analysis</topic><topic>Protective Agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Samojlik, Isidora</creatorcontrib><creatorcontrib>Lakić, Neda</creatorcontrib><creatorcontrib>Mimica-Dukić, Neda</creatorcontrib><creatorcontrib>Đaković-Švajcer, Kornelia</creatorcontrib><creatorcontrib>Božin, Biljana</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Samojlik, Isidora</au><au>Lakić, Neda</au><au>Mimica-Dukić, Neda</au><au>Đaković-Švajcer, Kornelia</au><au>Božin, Biljana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae)</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2010-08-11</date><risdate>2010</risdate><volume>58</volume><issue>15</issue><spage>8848</spage><epage>8853</epage><pages>8848-8853</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>Essential oils of Coriandrum sativum L. and Carum carvi L. fruits were analyzed by gas chromatography−mass spectrometry and assayed for their in vitro and in vivo antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl4) damage. The in vitro antioxidant activity was evaluated as a free radical scavenging capacity (RSC), measured as scavenging activity of the essential oils on 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and OH radicals and effects on lipid peroxidation (LP) in two systems of induction. Some liver biochemical parameters were determined in animals pretreated with essential oils and later intoxicated with CCl4 to assess in vivo hepatoprotective effect. Tested essential oils were able to reduce the stable DPPH• in a dose-dependent manner and to neutralize H2O2, reaching 50% neutralization with IC50 values of <2.5 μL/mL for Carvi aetheroleum and 4.05 μL/mL for Coriandri aetheroleum. Caraway essential oil strongly inhibited LP in both systems of induction, whereas coriander essential oil exhibited prooxidant activity. In vivo investigation conferred leak of antioxidative capacity of coriander essential oil, whereas the essential oil of caraway appeared promising for safe use in folk medicine and the pharmaceutical and food industries.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>20608729</pmid><doi>10.1021/jf101645n</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8561 |
| ispartof | Journal of agricultural and food chemistry, 2010-08, Vol.58 (15), p.8848-8853 |
| issn | 0021-8561 1520-5118 |
| language | eng |
| recordid | cdi_crossref_primary_10_1021_jf101645n |
| source | American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list) |
| subjects | Animals antioxidant activity Antioxidants - administration & dosage Antioxidants - analysis Aroma and flavouring agent industries Biological and medical sciences caraway Carum - chemistry Carum carvi Coriandrum - chemistry Coriandrum sativum essential oils food analysis Food Chemistry/Biochemistry food composition Food industries Fundamental and applied biological sciences. Psychology hepatoprotective effect Lipid Peroxidation - drug effects Liver - drug effects Liver - metabolism Male Mice Oils, Volatile - administration & dosage Oils, Volatile - analysis Plant Oils - administration & dosage Plant Oils - analysis Protective Agents |
| title | Antioxidant and Hepatoprotective Potential of Essential Oils of Coriander (Coriandrum sativum L.) and Caraway (Carum carvi L.) (Apiaceae) |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T23%3A17%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-acs_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antioxidant%20and%20Hepatoprotective%20Potential%20of%20Essential%20Oils%20of%20Coriander%20(Coriandrum%20sativum%20L.)%20and%20Caraway%20(Carum%20carvi%20L.)%20(Apiaceae)&rft.jtitle=Journal%20of%20agricultural%20and%20food%20chemistry&rft.au=Samojlik,%20Isidora&rft.date=2010-08-11&rft.volume=58&rft.issue=15&rft.spage=8848&rft.epage=8853&rft.pages=8848-8853&rft.issn=0021-8561&rft.eissn=1520-5118&rft.coden=JAFCAU&rft_id=info:doi/10.1021/jf101645n&rft_dat=%3Cacs_cross%3Ea68579799%3C/acs_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-a474t-6ce0fd8774abedea0fb5e17ef70f34bc0739796ef0c6ef513590c96e150caaf13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/20608729&rfr_iscdi=true |