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Discovery of 1-[3-(Aminomethyl)phenyl]- N -[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1 H -pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

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Bibliographic Details
Published in:Journal of medicinal chemistry 2001-02, Vol.44 (4), p.566-578
Main Authors: Pinto, Donald J. P., Orwat, Michael J., Wang, Shuaige, Fevig, John M., Quan, Mimi L., Amparo, Eugene, Cacciola, Joseph, Rossi, Karen A., Alexander, Richard S., Smallwood, Angela M., Luettgen, Joseph M., Liang, Li, Aungst, Bruce J., Wright, Matthew R., Knabb, Robert M., Wong, Pancras C., Wexler, Ruth R., Lam, Patrick Y. S.
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm000409z