3-(2-Carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex

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Bibliographic Details
Published in:Journal of medicinal chemistry 1990-11, Vol.33 (11), p.2944-2946
Main Authors: Salituro, Francesco G, Harrison, Boyd L, Baron, Bruce M, Nyce, Philip L, Stewart, Kenneth T, McDonald, Ian A
Format: Article
Language:English
Subjects:
Animals
Binding Sites
Binding, Competitive
Cerebral Cortex - metabolism
Glycine - metabolism
Hippocampus - metabolism
Indoles - chemical synthesis
Indoles - metabolism
Indoles - pharmacology
Molecular Structure
N-Methylaspartate - antagonists & inhibitors
Propionates - chemical synthesis
Propionates - metabolism
Propionates - pharmacology
Rats
Receptors, N-Methyl-D-Aspartate - metabolism
Structure-Activity Relationship
Strychnine - pharmacology
Citations: Items that cite this one
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Description
Summary:
ISSN:0022-2623
1520-4804
DOI:10.1021/jm00173a003