Conformationally Constrained Analogues of Diacylglycerol. 18. The Incorporation of a Hydroxamate Moiety into Diacylglycerol-Lactones Reduces Lipophilicity and Helps Discriminate between sn-1 and sn-2 Binding Modes to Protein Kinase C (PK-C). Implications for Isozyme Specificity

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Bibliographic Details
Published in:Journal of medicinal chemistry 2003-06, Vol.46 (13), p.2794-2794
Main Authors: Lee, Jeewoo, Han, Kee-Chung, Kang, Ji-Hye, Pearce, Larry L, Lewin, Nancy E, Yan, Shunqi, Benzaria, Samira, Nicklaus, Marc C, Blumberg, Peter M, Marquez, Victor E
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm030167d