Stereoselective Preparation of N -[( R,R )-( E )-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl- N -methyl-3,5-bis(trifluoromethyl)benzamide, a Potent and Orally Active Dual Neurokinin NK 1 /NK 2 Receptor Antagonist

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Bibliographic Details
Published in:Journal of medicinal chemistry 2003-07, Vol.46 (16), p.3508-3513
Main Authors: Gerspacher, Marc, Lewis, Christine, Ball, Howard A., Howes, Colin, Subramanian, Natarajan, Ryffel, Karin, Fozard, John R.
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm030786m