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Discovery, Structure−Activity Relationship, and Pharmacological Evaluation of (5-Substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as Potent Dipeptidyl Peptidase IV Inhibitors

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Bibliographic Details
Published in:Journal of medicinal chemistry 2006-08, Vol.49 (17), p.5387-5387
Main Authors: Pei, Zhonghua, Li, Xiaofeng, Longenecker, Kenton, von Geldern, Thomas W, Wiedeman, Paul E, Lubben, Thomas H, Zinker, Bradley A, Stewart, Kent, Ballaron, Stephen J, Stashko, Michael A, Mika, Amanda K, Beno, David W. A, Long, Michelle, Wells, Heidi, Kempf-Grote, Anita J, Madar, David J, McDermott, Todd S, Bhagavatula, Lakshmi, Fickes, Michael G, Pireh, Daisy, Solomon, Larry R, Lake, Marc R, Edalji, Rohinton, Fry, Elizabeth H, Sham, Hing L, Trevillyan, James M
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm060818g