Discovery of N -((4-([1,2,4]Triazolo[1,5- a ]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1 H -imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent

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Bibliographic Details
Published in:Journal of medicinal chemistry 2014-05, Vol.57 (10), p.4213-4238
Main Authors: Jin, Cheng Hua, Krishnaiah, Maddeboina, Sreenu, Domalapally, Subrahmanyam, Vura B., Rao, Kota S., Lee, Hwa Jeong, Park, So-Jung, Park, Hyun-Ju, Lee, Kiho, Sheen, Yhun Yhong, Kim, Dae-Kee
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm500115w