Discovery of 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2 H -pyrazolo[3,4- f ][1,4]oxazepin-8(5 H )-one (PF-514273), a Novel, Bicyclic Lactam-Based Cannabinoid-1 Receptor Antagonist for the Treatment of Obesity

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Bibliographic Details
Published in:Journal of medicinal chemistry 2009-05, Vol.52 (9), p.2652-2655
Main Authors: Dow, Robert L., Carpino, Philip A., Hadcock, John R., Black, Shawn C., Iredale, Philip A., DaSilva-Jardine, Paul, Schneider, Steven R., Paight, Ernest S., Griffith, David A., Scott, Dennis O., O’Connor, Rebecca E., Nduaka, Chudy I.
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm900255t