4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist

Saved in:
Bibliographic Details
Published in:Journal of medicinal chemistry 2000-02, Vol.43 (3), p.449-456
Main Authors: He, Liqi, Gilligan, Paul J., Zaczek, Robert, Fitzgerald, Lawrence W., McElroy, John, Shen, H-S. L., Saye, Jo Anne, Kalin, Ned H., Shelton, Steven, Christ, David, Trainor, George, Hartig, Paul
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03
cites cdi_FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03
container_end_page 456
container_issue 3
container_start_page 449
container_title Journal of medicinal chemistry
container_volume 43
creator He, Liqi
Gilligan, Paul J.
Zaczek, Robert
Fitzgerald, Lawrence W.
McElroy, John
Shen, H-S. L.
Saye, Jo Anne
Kalin, Ned H.
Shelton, Steven
Christ, David
Trainor, George
Hartig, Paul
description
doi_str_mv 10.1021/jm9904351
format article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1021_jm9904351</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1021_jm9904351</sourcerecordid><originalsourceid>FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03</originalsourceid><addsrcrecordid>eNo9kM1KAzEcxIMoWKsH3yDHFjaaf5L98larVUGolN5Elv9uU5uS3SzZRdyevPoUvptP4vqBp5lhht9hCDkFfgZcwPm2TFOuZAh7ZACh4EwlXO2TAedCMBEJeUiOmmbLOZcg5IB8KDaCQLIrU-p241672ruaCdZZLE3lxkwEMVv9lJ1lCRuJQPW52FjXDze66uy47jzunHWPEISMIn1iPbG3rTe4M5W--Hx7pxP64FpdtQGde7S2o5fG4Qsai7nVdLqYUaALXei6dZ5OqhafXWWa9pgcrNE2-uRPh2Q5u15Ob9n9_OZuOrlnRayARTqOQaYCEpQpz0MtVa4S4ElYJJBLjOV6FYeqSAsuc4gUqghXudSgMS8i5HJIxr_Ywrum8Xqd1d6U6LsMePZ9bPZ_rPwC8AdpTQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist</title><source>American Chemical Society:Jisc Collections:American Chemical Society Read &amp; Publish Agreement 2022-2024 (Reading list)</source><creator>He, Liqi ; Gilligan, Paul J. ; Zaczek, Robert ; Fitzgerald, Lawrence W. ; McElroy, John ; Shen, H-S. L. ; Saye, Jo Anne ; Kalin, Ned H. ; Shelton, Steven ; Christ, David ; Trainor, George ; Hartig, Paul</creator><creatorcontrib>He, Liqi ; Gilligan, Paul J. ; Zaczek, Robert ; Fitzgerald, Lawrence W. ; McElroy, John ; Shen, H-S. L. ; Saye, Jo Anne ; Kalin, Ned H. ; Shelton, Steven ; Christ, David ; Trainor, George ; Hartig, Paul</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>DOI: 10.1021/jm9904351</identifier><language>eng</language><ispartof>Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.449-456</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03</citedby><cites>FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>He, Liqi</creatorcontrib><creatorcontrib>Gilligan, Paul J.</creatorcontrib><creatorcontrib>Zaczek, Robert</creatorcontrib><creatorcontrib>Fitzgerald, Lawrence W.</creatorcontrib><creatorcontrib>McElroy, John</creatorcontrib><creatorcontrib>Shen, H-S. L.</creatorcontrib><creatorcontrib>Saye, Jo Anne</creatorcontrib><creatorcontrib>Kalin, Ned H.</creatorcontrib><creatorcontrib>Shelton, Steven</creatorcontrib><creatorcontrib>Christ, David</creatorcontrib><creatorcontrib>Trainor, George</creatorcontrib><creatorcontrib>Hartig, Paul</creatorcontrib><title>4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist</title><title>Journal of medicinal chemistry</title><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNo9kM1KAzEcxIMoWKsH3yDHFjaaf5L98larVUGolN5Elv9uU5uS3SzZRdyevPoUvptP4vqBp5lhht9hCDkFfgZcwPm2TFOuZAh7ZACh4EwlXO2TAedCMBEJeUiOmmbLOZcg5IB8KDaCQLIrU-p241672ruaCdZZLE3lxkwEMVv9lJ1lCRuJQPW52FjXDze66uy47jzunHWPEISMIn1iPbG3rTe4M5W--Hx7pxP64FpdtQGde7S2o5fG4Qsai7nVdLqYUaALXei6dZ5OqhafXWWa9pgcrNE2-uRPh2Q5u15Ob9n9_OZuOrlnRayARTqOQaYCEpQpz0MtVa4S4ElYJJBLjOV6FYeqSAsuc4gUqghXudSgMS8i5HJIxr_Ywrum8Xqd1d6U6LsMePZ9bPZ_rPwC8AdpTQ</recordid><startdate>20000201</startdate><enddate>20000201</enddate><creator>He, Liqi</creator><creator>Gilligan, Paul J.</creator><creator>Zaczek, Robert</creator><creator>Fitzgerald, Lawrence W.</creator><creator>McElroy, John</creator><creator>Shen, H-S. L.</creator><creator>Saye, Jo Anne</creator><creator>Kalin, Ned H.</creator><creator>Shelton, Steven</creator><creator>Christ, David</creator><creator>Trainor, George</creator><creator>Hartig, Paul</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20000201</creationdate><title>4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist</title><author>He, Liqi ; Gilligan, Paul J. ; Zaczek, Robert ; Fitzgerald, Lawrence W. ; McElroy, John ; Shen, H-S. L. ; Saye, Jo Anne ; Kalin, Ned H. ; Shelton, Steven ; Christ, David ; Trainor, George ; Hartig, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>He, Liqi</creatorcontrib><creatorcontrib>Gilligan, Paul J.</creatorcontrib><creatorcontrib>Zaczek, Robert</creatorcontrib><creatorcontrib>Fitzgerald, Lawrence W.</creatorcontrib><creatorcontrib>McElroy, John</creatorcontrib><creatorcontrib>Shen, H-S. L.</creatorcontrib><creatorcontrib>Saye, Jo Anne</creatorcontrib><creatorcontrib>Kalin, Ned H.</creatorcontrib><creatorcontrib>Shelton, Steven</creatorcontrib><creatorcontrib>Christ, David</creatorcontrib><creatorcontrib>Trainor, George</creatorcontrib><creatorcontrib>Hartig, Paul</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>He, Liqi</au><au>Gilligan, Paul J.</au><au>Zaczek, Robert</au><au>Fitzgerald, Lawrence W.</au><au>McElroy, John</au><au>Shen, H-S. L.</au><au>Saye, Jo Anne</au><au>Kalin, Ned H.</au><au>Shelton, Steven</au><au>Christ, David</au><au>Trainor, George</au><au>Hartig, Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist</atitle><jtitle>Journal of medicinal chemistry</jtitle><date>2000-02-01</date><risdate>2000</risdate><volume>43</volume><issue>3</issue><spage>449</spage><epage>456</epage><pages>449-456</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><doi>10.1021/jm9904351</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-2623
ispartof Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.449-456
issn 0022-2623
1520-4804
language eng
recordid cdi_crossref_primary_10_1021_jm9904351
source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
title 4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5- a ]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF 1 Receptor Antagonist
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T10%3A49%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo%5B1,5-%20a%20%5D-1,3,5-triazine:%E2%80%89%20A%20Potent,%20Orally%20Bioavailable%20CRF%201%20Receptor%20Antagonist&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=He,%20Liqi&rft.date=2000-02-01&rft.volume=43&rft.issue=3&rft.spage=449&rft.epage=456&rft.pages=449-456&rft.issn=0022-2623&rft.eissn=1520-4804&rft_id=info:doi/10.1021/jm9904351&rft_dat=%3Ccrossref%3E10_1021_jm9904351%3C/crossref%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c741-6e77139218a390b5e34b481085c81b3a73fd754c9c03b164a46adb3e1eabc6a03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true