Formation of Multilayer Composite Particles Comprised of Silica/Vesicle/Silica Particles by Heterocoagulation

The multilayer composite particles comprised of silica/PC (phosphatidylcholine) vesicle/silica particles have been prepared by using the heterocoagulation technique. The formation process is as follows:  at first, large silica particles (2r = 1.5 μm) and PC vesicles (2r = 0.2 μm) were mixed at a def...

Full description

Saved in:
Bibliographic Details
Published in:Langmuir 2001-04, Vol.17 (8), p.2283-2286
Main Authors: Yang, Bo, Matsumura, Hideo, Katoh, Kaoru, Kise, Hideo, Furusawa, Kunio
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The multilayer composite particles comprised of silica/PC (phosphatidylcholine) vesicle/silica particles have been prepared by using the heterocoagulation technique. The formation process is as follows:  at first, large silica particles (2r = 1.5 μm) and PC vesicles (2r = 0.2 μm) were mixed at a definite particle number ratio in 10-4 M LaCl3 aqueous solution. The PC vesicle/silica composites were spontaneously formed by mutual electrostatic attraction. After removal of the excess PC vesicles from the system, the small silica particle (2r = 0.5 μm) suspension was added into the PC vesicle/silica composite dispersions to form the multilayer composite particles composed of small silica, PC vesicle, and core silica particles. The formation of multilayer composite particles was confirmed by the electrophoresis, dynamic light scattering (DLS), and adsorption measurements of PC molecules. Finally, the existence of multilayers was confirmed directly using a special optical microscope.
ISSN:0743-7463
1520-5827
DOI:10.1021/la001088x