Decipinin A and Decipienolides A and B:  New Bioactive Metabolites from the Coprophilous Fungus Podospora d ecipiens

Decipinin A (1), a new compound with antifungal and antibacterial activity, has been isolated from liquid cultures of the coprophilous fungus Podospora decipiens (JS 270). Two new tetracyclic sesquiterpene lactones, decipienolides A (2) and B (3), were also obtained from this isolate as an inseparab...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2002-06, Vol.65 (6), p.916-919
Main Authors: Che, Yongsheng, Gloer, James B, Koster, Brenda, Malloch, David
Format: Article
Language:English
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Summary:Decipinin A (1), a new compound with antifungal and antibacterial activity, has been isolated from liquid cultures of the coprophilous fungus Podospora decipiens (JS 270). Two new tetracyclic sesquiterpene lactones, decipienolides A (2) and B (3), were also obtained from this isolate as an inseparable mixture of epimers that showed antibacterial activity. The structures of 1−3 were elucidated by analysis of 1D and 2D NMR data, aided by chemical shift comparisons to related compounds.
ISSN:0163-3864
1520-6025
DOI:10.1021/np010575p