Xenia Diterpenoids from the Formosan Soft Coral Xenia b lumi

Eight new xenia diterpenoids, blumiolide-A (1) (novel carbon skeleton), blumiolide-B (2), 9-deoxy-isoxeniolide-A (3), 9-deoxy-7,8-epoxy-isoxeniolide-A (4), 9-deacetoxy-7,8-epoxy-13-epi-xenicin (5), 9-deoxy-7,8-epoxy-xeniolide-A (6), blumiolide-C (7), and blumicin-A (8), were isolated from the methyl...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2005-09, Vol.68 (9), p.1336-1340
Main Authors: El-Gamal, Ali A. H., Chiang, Chin-Ying, Huang, Shin-Huei, Wang, Shang-Kwei, Duh, Chang-Yih
Format: Article
Language:English
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Summary:Eight new xenia diterpenoids, blumiolide-A (1) (novel carbon skeleton), blumiolide-B (2), 9-deoxy-isoxeniolide-A (3), 9-deoxy-7,8-epoxy-isoxeniolide-A (4), 9-deacetoxy-7,8-epoxy-13-epi-xenicin (5), 9-deoxy-7,8-epoxy-xeniolide-A (6), blumiolide-C (7), and blumicin-A (8), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia blumi. Their structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
ISSN:0163-3864
1520-6025
DOI:10.1021/np058047r