Antifungal Activity of Trillium grandiflorum Constituents

EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1988-01, Vol.51 (1), p.94-98
Main Authors: Hufford, Charles D, Liu, Shihchih, Clark, Alice M
Format: Article
Language:English
Subjects:
Animals
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Antifungal Agents - toxicity
Biological and medical sciences
Candidiasis - drug therapy
COMPOSICION
COMPOSITION
FONGICIDE
Fungi - drug effects
FUNGICIDAS
FUNGICIDES
General pharmacology
LILIACEAE
Magnetic Resonance Spectroscopy
Medical sciences
Mice
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Plant Extracts - toxicity
Plants, Medicinal - analysis
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Description
Summary:EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.
ISSN:0163-3864
1520-6025
DOI:10.1021/np50055a013