Swinholides and New Acetylenic Compounds from an Undescribed Species of Theonella Sponge

Four new acetylenic compounds, 5 − 8, along with four known ones, 1 − 4, were isolated from a sponge, Theonella sp., collected in Chuuk Atoll, Federated States of Micronesia. Three unrelated swinholide-type compounds were also isolated. The structures of the new acetylenes were determined from spect...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1999-09, Vol.62 (9), p.1336-1338
Main Authors: Fu, Xiong, Schmitz, Francis J, Kelly, Michelle
Format: Article
Language:English
Subjects:
acetogenins
acetylene
Acetylene - chemistry
Acetylene - isolation & purification
Animals
Biological and medical sciences
chemical composition
chemical structure
derivatives
General pharmacology
Marine Toxins - chemistry
Marine Toxins - isolation & purification
Medical sciences
Molecular Structure
parazoa
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Porifera - chemistry
secondary metabolites
spectral analysis
Spectrum Analysis
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Summary:Four new acetylenic compounds, 5 − 8, along with four known ones, 1 − 4, were isolated from a sponge, Theonella sp., collected in Chuuk Atoll, Federated States of Micronesia. Three unrelated swinholide-type compounds were also isolated. The structures of the new acetylenes were determined from spectral data and chemical degradation.
ISSN:0163-3864
1520-6025
DOI:10.1021/np990167+