New Boronic Acid Fluorescent Reporter Compounds. 2. A Naphthalene-Based On−Off Sensor Functional at Physiological pH

A new boronic acid fluorescent on−off reporter compound (1) was synthesized. This fluorescent sensor shows a 41-fold emission intensity increase upon addition of 50 mM fructose in 0.1 M aqueous phosphate buffer at pH 7.4.

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Bibliographic Details
Published in:Organic letters 2003-11, Vol.5 (24), p.4615-4618
Main Authors: Gao, Xingming, Zhang, Yanling, Wang, Binghe
Format: Article
Language:English
Subjects:
1-Naphthylamine - analogs & derivatives
1-Naphthylamine - chemical synthesis
1-Naphthylamine - chemistry
Boron - chemistry
Boronic Acids - chemical synthesis
Boronic Acids - chemistry
Carbohydrates - chemistry
Fluorescence
Hydrogen-Ion Concentration
Magnetic Resonance Spectroscopy
Molecular Structure
Naphthalenes - chemistry
Spectrometry, Fluorescence
Titrimetry
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Description
Summary:A new boronic acid fluorescent on−off reporter compound (1) was synthesized. This fluorescent sensor shows a 41-fold emission intensity increase upon addition of 50 mM fructose in 0.1 M aqueous phosphate buffer at pH 7.4.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol035783i