Adsorbent Screening for Metal Impurity Removal in Pharmaceutical Process Research

A microtube screening approach affords simple and convenient assessment of the selective adsorption of metal impurities by a variety of different process adsorbents. This approach is helpful in identifying rapid solutions to metal impurity problems in pharmaceutical process research. Several example...

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Bibliographic Details
Published in:Organic process research & development 2005-03, Vol.9 (2), p.198-205
Main Authors: Welch, Christopher J, Albaneze-Walker, Jennifer, Leonard, William R, Biba, Mirlinda, DaSilva, Jimmy, Henderson, Derek, Laing, Brian, Mathre, David J, Spencer, Sandra, Bu, Xiaodong, Wang, Tiebang
Format: Article
Language:English
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Summary:A microtube screening approach affords simple and convenient assessment of the selective adsorption of metal impurities by a variety of different process adsorbents. This approach is helpful in identifying rapid solutions to metal impurity problems in pharmaceutical process research. Several examples illustrating the utility of the approach are presented.
ISSN:1083-6160
1520-586X
DOI:10.1021/op049764f