Facile Synthesis of 5,6-Dimethoxy-1-tetralone

A facile synthesis of 5,6-dimethoxy-1-tetralone, a key intermediate in the synthesis of an antidepressant compound, ABT-200, was developed from the inexpensive starting material guaiacol.

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Bibliographic Details
Published in:Organic process research & development 1999-01, Vol.3 (1), p.71-72
Main Authors: Lahiri, Saswata, Ramarao, C, Rao, B. Venkateswara, Rama Rao, A. V, Chorghade, Mukund S
Format: Article
Language:English
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Description
Summary:A facile synthesis of 5,6-dimethoxy-1-tetralone, a key intermediate in the synthesis of an antidepressant compound, ABT-200, was developed from the inexpensive starting material guaiacol.
ISSN:1083-6160
1520-586X
DOI:10.1021/op970111r