Early Injury of Chromoexcretion after Total Irradiation of Rats

IT is claimed by all available literature that damage occurs to the function of the liver after whole-body irradiation by doses, approaching LD 100, from as late as the stage of development of the secondary post-radiation changes 1,2 . Some biochemical results, however, support the opinion that the...

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Bibliographic Details
Published in:Nature (London) 1960-02, Vol.185 (4713), p.630-631
Main Authors: DIENSTBIER, ZDEN K, ANDRYSEK, OSKAR
Format: Article
Language:English
Subjects:
Animals
Coloring Agents - metabolism
Humanities and Social Sciences
letter
Liver - radiation effects
multidisciplinary
Radiation Injuries, Experimental
Rats
Science
Science (multidisciplinary)
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Summary:IT is claimed by all available literature that damage occurs to the function of the liver after whole-body irradiation by doses, approaching LD 100, from as late as the stage of development of the secondary post-radiation changes 1,2 . Some biochemical results, however, support the opinion that the liver cell should be damaged in its function at the earliest stage of an acute irradiation disturbance 3–5 . To prove the early functional lesion we carried out experiments with bengal rose tagged with radioactive iodine-131.
ISSN:0028-0836
1476-4687
DOI:10.1038/185630a0