Sub-cellular Distribution of the Substance P in the Nervous Tissues

Hebb and Whittaker 1 have described the isolation of a sub-cellular fraction of brain tissue which contains bound acetylcholine and choline acetylase. This fraction was examined further by Whittaker 2 with equilibrium centrifugation in a density gradient. His results appear to provide evidence for p...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 1962-02, Vol.193 (4815), p.585-585
Main Authors: INOUYE, AKIRA, KATAOKA, KIYOSHI
Format: Article
Language:English
Subjects:
Humanities and Social Sciences
letter
multidisciplinary
Science
Science (multidisciplinary)
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hebb and Whittaker 1 have described the isolation of a sub-cellular fraction of brain tissue which contains bound acetylcholine and choline acetylase. This fraction was examined further by Whittaker 2 with equilibrium centrifugation in a density gradient. His results appear to provide evidence for physiological significance of his “synaptic vesicle fraction”. We have also attempted to apply his fractionation method to study sub-cellular distribution of substance P in the nervous system.
ISSN:0028-0836
1476-4687
DOI:10.1038/193585a0