Sub-cellular Distribution of the Substance P in the Nervous Tissues

Hebb and Whittaker 1 have described the isolation of a sub-cellular fraction of brain tissue which contains bound acetylcholine and choline acetylase. This fraction was examined further by Whittaker 2 with equilibrium centrifugation in a density gradient. His results appear to provide evidence for p...

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Published in:Nature (London) 1962-02, Vol.193 (4815), p.585-585
Main Authors: INOUYE, AKIRA, KATAOKA, KIYOSHI
Format: Article
Language:English
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multidisciplinary
Science
Science (multidisciplinary)
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description Hebb and Whittaker 1 have described the isolation of a sub-cellular fraction of brain tissue which contains bound acetylcholine and choline acetylase. This fraction was examined further by Whittaker 2 with equilibrium centrifugation in a density gradient. His results appear to provide evidence for physiological significance of his “synaptic vesicle fraction”. We have also attempted to apply his fractionation method to study sub-cellular distribution of substance P in the nervous system.
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Science
Science (multidisciplinary)
title Sub-cellular Distribution of the Substance P in the Nervous Tissues
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